All opioids can impair the psychological or physical talents demanded for that performance of probably dangerous responsibilities like driving or functioning machinery if taken in huge doses.[fifteen][sixteen]
Naloxone should not be administered while in the absence of clinically significant respiratory or circulatory depression secondary to dihydrocodeine overdosage.
Hyperalgesia Hyperalgesia may be diagnosed If your patient on long-term opioid therapy presents with elevated pain. This might be qualitatively and anatomically unique from pain relevant to disease development or to breakthrough pain ensuing from development of opioid tolerance.
- You have taken it in accordance with the Guidelines supplied with the prescriber and within the information provided with the medicine and
When dihydrocodeine is taken concomitantly with antipsychotics there could possibly be a heightened sedative and hypotensive impact. Concomitant utilization of dihydrocodeine and ritonavir needs to be avoided on account of the chance of toxicity.
Bệnh nhân suy gan hoặc suy thận nên tránh sử dụng hoặc giảm liều dihydrocodeine nếu không cần thiết.
depression, coma and Demise. Thanks to these risks, concomitant prescribing with these sedative medicines must be reserved for patients for whom alternative treatment choices are impossible.
four.five Interaction with other medicinal products and other forms of interaction The concomitant utilization of opioids with sedative medicines which include benzodiazepines or linked drugs raises the danger of sedation, respiratory depression, coma and Demise due to additive CNS depressant outcome.
Regular use during pregnancy may website lead to drug dependence while in the foetus, leading to withdrawal symptoms within the neonate.
Nearly all patients taken care of with chlorpheniramine knowledge drowsiness. This drowsiness may well subside in a few patients with extended use.
Gastrointestinal side effects of chlorpheniramine have incorporated dry mouth and constipation in up to one-third of addressed patients.
Get medical help without delay for those who have any extremely significant side effects, which include: fainting, seizure.
FDB Multilex and people who are answerable for their design, operation and upkeep have no idea the particular situation, situation or medical historical past of individual patients or groups of patients and so simply cannot suggest regarding certain cases.
Normally speak to your healthcare provider to make sure the information exhibited on this page applies to your individual situations.